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Consistent Product
PerformanceRarely are solvents used on
their own in the laboratory. Invariably, they're used to
bring into solution the sample to be analysed or the
reactants to be reacted together. Also, many solvents
themselves are used as mixtures, for example as eluants
in HPLC or as extraction and reference mixtures in GC.
ROMIL have
long provided an optional service whereby ready-to-use
solvent mixtures are made up to customer specifications.
Such a service finds favour in routine QC where methods
are established on defined mixtures and which must be
made in large volumes.
| HPLC
Eluants |
Mixtures are
made from our ROMIL-SpS™
and similar materials thus ensuring a consistent
performance. For example, HPLC eluants are often
made up with commercial solvents combined with in-house
produced water. Without sufficient in-house
control on the quality of this water, the
performance of the whole mixture is impaired. In our
experience reagent quality should be matched
across the individual components of a mixture.
Otherwise, the quality degenerates to the least
pure constituent. This is often the case of HPLC
eluants where the quality of the in-house
produced water is not sufficiently controlled to
maintain the quality of the mixture and this can
result in time wasting chasing of ghost peaks and
complaints to the supplier of the solvent. That
is not to say that commercial laboratory water
purifiers cannot produce the highest quality
water. They can. But to do that reliably not only
requires the investment in the purification
equipment itself, but also an on-going system of
regular maintenance and strict quality control of
the output.
Sourcing your
HPLC eluants from ROMIL ensures consistency of
product performance and also reduces costs which
are otherwise incurred in the handling of
hazardous solvents in the QC laboratory.
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| GC
Calibration mixes |
Again, in the QC
laboratory extensive use may be made of
proprietary solvent mixes as reference materials
in GC analysis of product quality in chemical and
pharmaceutical production. Indeed, the regular ROMIL-SpS™
solvents themselves may be used as reliable and
cost effective reference materials for gas
chromatography, being generally specified to a
minimum 99.9% purity and available in convenient
500ml packs. Mixtures may be
made up from ROMIL-SpS™
solvents using balances calibrated with weights
traceable to the internationally recognised SI
units. So in many respects it can be advantageous
to out-source the production of such materials to
an organisation such as ROMIL which has both the
required expertise as well as direct access to
and control of the pure components.
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| Custom
Mixes |
Ask for a
quotation for your own specific mixture. Just
give us the following information:
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- Detailed
recipe (including concentration
tolerances of ingredients)
- Grades
of solvent required (see SpS
solvents section)
- Preferred
pack size (choose amber glass bottles or
returnable stainless steel flasks)
- Annual
quantity / quantity per order (the larger
the quantity, the lower the price)
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| email: quote.me@romil.com |
Let ROMIL save
you time and money in making up these complex
mixtures. |
The following pages list examples of
mixtures which have been produced to customer order and
give an idea of what can be done.
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